anndict.annotate.harmony_label_transfer

anndict.annotate.harmony_label_transfer(origin_adata, destination_adata, origin_subset_column, label_column)

Perform Harmony integration and transfer labels from origin_adata to destination_adata.

This function subsets origin_adata based on a provided column to get the cells that match in the same column of destination_adata. It then performs Harmony integration on the combined dataset and transfers the specified label column from origin_adata to destination_adata.

Parameters:

origin_adata AnnData

The origin AnnData object containing the reference data and labels.

destination_adata AnnData

The AnnData object to which labels will be transferred.

origin_subset_column str

The column name in origin_adata.obs used for subsetting origin_adata to match destination_adata.

label_column str

The column name in origin_adata.obs containing the labels to be transferred.

Return type:

None

Returns:

None

Notes

Modifies destination_adata in-place, adding a new column ‘harmony_labels’ in adata_to_label.obs containing the transferred labels.